Annabelle Wallis

Madison Mitchell

Maddie Hasson

Sydney Lake

George Young

Detective Kekoa Shaw

Michole Briana White

Detective Regina Moss

Susanna Thompson

Jeanne

Ingrid Bisu

Winnie

Jean Louisa Kelly

Jane Doe

Jake Abel

Derek Mitchell

Jacqueline McKenzie

Dr. Florence Weaver

Christian Clemenson

Dr. Victor Fields

Amir Aboulela

Dr. Gregory

Mercedes Colon

Mendez

Ruben Pla

Officer Rubin

Jon Lee Brody

Officer Lee

Paula Marshall

Beverly Woods

Zoë Bell

Scorpion

Shaunte Lynette Johnson

Beta

Natalia Safran

Nurse Annie

Mike Mendez

Hospital Security Guard #1

Randy Haynie

Hospital Security Guard #2

Cord Walker

Hospital Security Guard #3

Jesus Trujillo

Research Doctor

Lisa Catara

Research Orderly

Danielle Nottingham

News Anchor

Ray Chase

Gabriel (voice)

Marina Mazepa

Gabriel

Mckenna Grace

Young Madison

Madison Wolfe

Young Serena

Andy Bean

Frank

Patricia Velásquez

Nurse Velasquez

Patrick Cox

Mr. Stanley (uncredited)

Gregory Garcia

Seattle Police Officer (uncredited)

Emir García

Mustang Driver (uncredited)

Renee Harbek

Caroline (uncredited)

Janet Hsieh

Nurse J. De Marco (uncredited)

Paul Mabon

Orderly (uncredited)

Gino Montesinos

Seattle Police Officer (uncredited)

Josh Rutgers

Referee (uncredited)

Halston Van Atta

Child Madison (uncredited)

Louise Van Veenendaal

Prisoner (uncredited)