Ben Stiller

Mr. Furious / Roy

Hank Azaria

Blue Raja / Jeffrey

William H. Macy

Shoveler / Eddie

Greg Kinnear

Captain Amazing / Lance

Kel Mitchell

Invisible Boy

Paul Reubens

Spleen

Janeane Garofalo

Bowler / Carol

Wes Studi

Sphinx

Claire Forlani

Monica

Geoffrey Rush

Casanova Frankenstein

Lena Olin

Dr. Anabel Leek

Suzy Eddie Izzard

Tony P

Tom Waits

Doc Heller

Artie Lange

Big Red

Louise Lasser

Violet

Ricky Jay

Vic Weems

Jenifer Lewis

Lucille

Pras Michel

Tony C

Ned Bellamy

Funk

Joel McCrary

McGuire

Ernie Lee Banks

Ted

Gerry Becker

Banyon

Corbin Bleu

Butch

Philip Bolden

Roland

Jake Cross

Thug

Emmy Laybourne

Reporter

Mason Lucero

Young Kid

Monet Mazur

Becky Beaner

Christopher Mugglebee

Reporter

Olivia Lauren Todd

Tracy

Frederick Usher

Thug

Kinka Usher

Moe

Gayle Vance

Sally

Adrian Armas

Disco Boy

Gichi Gamba

Disco Boy

Thomas Lake

Disco Boy

Robert Musselman

Disco Boy / Ballerinaman

Solo Scott

Disco Boy

Erik Michael Tristan

Disco Boy

James Duke

Big Tobacco