Tom Cruise

Barry Seal

Domhnall Gleeson

Monty 'Schafer'

Sarah Wright

Lucy Seal

Jesse Plemons

Sheriff Downing

Caleb Landry Jones

JB

Lola Kirke

Judy Downing

Jayma Mays

Dana Sibota

Alejandro Edda

Jorge Ochoa

Benito Martinez

James Rangel

E. Roger Mitchell

Agent Craig McCall

Jed Rees

Louis Finkle

Fredy Yate

Carlos Lehder

Mauricio Mejía

Pablo Escobar

Robert Farrior

Oliver North

Morgan Hinkleman

Christina

Alberto Ospino

Manuel Noriega

Felipe Bernedette

Translator

Daniel Lugo

Adolfo Calero

Jayson Warner Smith

Bill Cooper (Snowbird #1)

William Mark McCullough

Pete (Snowbird #2)

April Billingsley

Stewardess

Lauren Boyd

Secretary

Lauren Revard

Teller

Marcus Hester

Parka

Mike Pniewski

Willie (State Police)

Frank Licari

DEA Agent #1

Alex Collins

ATF #1

Scott Poythress

ATF #2

Connor Trinneer

George W. Bush / Texan

Alpha Trivette

Judge Linkletter

Kevin L. Johnson

Agent Horace Wainwright

DeVere Jehl

Plains Clothed Man

Emilio Sierra

Héctor (Colombian Driver)

Leon Lamar

Elderly Man

Tony Guerrero

Federico Vaughan

Maria Howell

NSC Woman

Darla Delgado

Customs Agent

Justice Leak

DEA Agent Winter

Robert Pralgo

Gary (Cubicle Mate)

Mickey Sumner

North's Aide Fawn Hall